Líneas de investigación, publicaciones y tesis finalizadas.

Líneas de investigación

  • Bioproducts for sustainable development, agriculture, and food industry

  • Biodegradation for clean-up of polluted environments

 Publicaciones 2018-2020

  1. Urtuvia Viviana, Villegas Pamela, Fuentes Sebastián, González Myriam, Seeger Michael. 2018. Burkholderia xenovorans LB400 possess a functional polyhydroxyalkanoate anabolic pathway and synthesizes poly(3-hydroxybutyrate) under nitrogen-limiting conditions. International Microbiology 21: 47. 
  2. Montenegro Iván, Madrid Alejandro, Cuellar Mauricio, Seeger Michael, Alfaro Juan Felipe, Besoain Ximena, Martínez Juan Pablo, Ramirez Ingrid, Olguín, Yusser, Valenzuela, Miryam. 2018. Biopesticide activity from drimanic compounds to control tomato pathogens. Molecules. 16: 23(8). 
  3. Orellana Roberto, Macaya Constanza, Bravo Guillermo, Dorochesi Flavia, Cumsille Andrés, Valencia Ricardo, Rojas Claudia, Seeger Michael. 2018. Living at the frontiers of life: extremophiles in Chile and their potential for bioremediation. Frontiers in Microbiology 9:1-24. 
  4. Méndez Valentina, Hernández Lisette, Salvà-Serra Francisco, Jaén-Luchoro, Daniel, Durán, Roberto E., Barra Bárbara, Piñeiro-Iglesias Beatriz, Moore, Edward R. B., Seeger Michael 2018. Complete genome sequence of the hydrocarbon-degrading strain Achromobacter sp. B7, isolated during petroleum hydrocarbon bioremediation in Valparaiso Region, Chile. Microbiology Resource Announcements. 7:e01326-18. 
  5. Concha Eric, Heipieper Hermann J, Wick Lukas Y, Ciudad Gustavo A, Navia Rodrigo. 2018. Effects of limonene, n‑decane and n‑decanol on growth and membrane fatty acid composition of the microalga Botryococcus braunii. AMB Express 8:189. 
  6. Valenzuela Miryam, Méndez Valentina, Montenegro Iván, Besoain Ximena, Seeger Michael. 2019. Streptomycin resistance in Clavibacter michiganensis subsp. michiganensis Chilean strains is related to rpsL gene mutation. Plant Pathology 68: 426-433. 
  7. Durán RE, Barra-Sanhueza B, Salvà-Serra F, Méndez V, Jaén-Luchoro D, Moore ERB, Seeger M. 2019. Complete genome sequence of the marine hydrocarbon degrader Alcaligenes aquatilis QD168, isolated from crude oil-polluted sediment of Quintero Bay, Central Chile. Microbiol Resour Announc 8:e01664-18. 
  8. Sanhueza C., Acevedo F., Rocha S., Villegas, P., Seeger M., Navia R. 2019. Polyhydroxyalkanoates as biomaterial for an electrospun scaffold. International Journal of Biological Macromolecules 124: 102-110 
  9. Durán Roberto E., Méndez Valentina, Barra-Sanhueza Bárbara, Rodríguez-Castro Laura, Salvà-Serra Francisco, Moore Edward R. B., Castro-Nallar, Eduardo, Seeger, Michael. 2019. Genomic and physiological traits of the marine bacterium Alcaligenes aquatilis QD168 isolated from Quintero Bay, Central Chile, reveal a robust adaptive response to environmental stressors. Frontiers in Microbiology 10: 528. 
  10. Alviz Gazitua Pablo, Fuentes-Albuquerque Sebastian, Rojas Luis A., Turner Raymond J, Guiliani Nicolas, Seeger Michael. 2019. The response of Cupriavidus metallidurans CH34 to cadmium involves inhibition of the initiation of biofilm formation, decrease in intracellular c-di-GMP levels and a novel metal regulated phosphodiesterase. Frontiers in Microbiology, Front. Microbiol. 10:1499. 
  11. Macaya CC, Méndez V, Durán RE, Aguila-Torres P, Salvà-Serra F, Jaén-Luchoro D, Moore ERB, Seeger M. 2019. Complete genome sequence of hydrocarbon-degrading halotolerant Acinetobacter radioresistens DD78, isolated from the Aconcagua River mouth in Central Chile. Microbiol Resour Announc 8:e00601-19. 
  12. Rodríguez-Castro Laura, Méndez Valentina, Durán Roberto E., Seeger Michael 2019. Long-chain flavodoxin FldX1 improves Paraburkholderia xenovorans LB400 tolerance to oxidative stress caused by paraquat and H2O2. PLoS ONE. 14(8): e0221881. 
  13. Claverías F, Gonzales-Siles L, Salvà-Serra F, Inganäs E, Molin K, Cumsille A, Undabarrena A, Couve E, Moore ERB, Gomila M, Cámara B. 2019 Corynebacterium alimapuense sp. nov., an obligate marine actinomycete isolated from sediment of Valparaíso bay, Chile. IJSEM 69(3):783-790. 
  14. Cea Mara, Gonzáleza, María Eugenia, Abarzúa Macarena, Navia Rodrigo 2019. Enzymatic esterification of oleic acid by Candida rugosa lipase immobilized onto biochar. Journal of Environmental Management 242: 171-177.
  15. Hidalgo P, Navia R, Hunterd R, Gonzalez ME, Echeverría A. 2019. Development of novel bio-based epoxides from microalgae Nannochloropsis gaditana lipids. Composites Part B 166:653-662. 
  16. Hildago-Oporto Pamela, Navia R, Hunter R, Coronado G, Gonzalez ME. 2019. Synthesis of carbon nanotubes using biochar as precursor material under microwave irradiation. Journal of Environmental Management 244:83-91. 
  17. Sankaranarayanan Sivashunmugam, Likozar Blaž, Navia Rodrigo. 2019. Real-time particle size analysis using the Focused Beam Reflectance Measurement probe for in situ fabrication of polyacrylamide-filler composite materials. Scientific Reports 9:10126. 
  18. Sankaranarayanan, S., Vishnukumar, P., Hariram, M., Vivekanandhan, S., Camus, C., Buschmann, A.H. and Navia, R. 2019. Hydrothermal synthesis, characterization and seed germination effects of green‐emitting graphene oxide‐carbon dot composite using brown macroalgal bio‐oil as precursor. J. Chem. Technol. Biotechnol., 94: 3269-3275. 
  19. Akkaya Ö, Nikel PI, Pérez-Pantoja D, de Lorenzo V. Evolving metabolism of 2,4-dinitrotoluene triggers SOS-independent diversification of host cells. Environ Microbiol. 2019 21(1):314-326. 
  20. Farkas Carlos, Donoso Raúl, Gárate-Castro Carla, Villegas Pamela, Durán Roberto E, Seeger Michael, Pérez-Pantoja, Danilo 2020. Draft genome sequence of two Pseudomonas strains that are able to use furan derivatives as only carbon source. Microbiology Resource Announcements 9:e01131-19. 
  21. Vasconez Ingrid Nicole, Besoain Ximena A., Vega-Celedón Paulina, Valenzuela Miryam, Seeger Michael. 2020, First Report of Bacterial Wilt Caused by Ralstonia solanacearum Phylotype IIB Sequevar 1 affecting tomato in different Regions of Chile. Plant Disease. Published Online: 11 Mar 2020. 
  22. Velásquez A, Vega-Celedón P, Fiaschi G, Agnolucci M, Avio L, Giovannetti M, D'Onofrio C, Seeger M. 2020. Responses of Vitis vinifera cv. Cabernet Sauvignon roots to the arbuscular mycorrhizal fungus Funneliformis mosseae and the plant growth-promoting rhizobacterium Ensifer meliloti include changes in volatile organic compounds. Mycorrhiza volume 30, pages 161-170(2020). 
  23. Velásquez Alexis, Valenzuela Miryam, Carvajal Marcela, Fiaschi Grazia, Avio Luciano, Giovannetti Manuela, D'Onofrio Claudio, Seeger Michael. 2020. The arbuscular mycorrhizal fungus Funneliformis mosseae induces changes and increases the concentration of volatile organic compounds in Vitis vinifera cv. Sangiovese leaf tissue. Plant Physiology and Biochemistry 155: 437-443. 
  24. Vilchez Ariel, Acevedo Francisca, Cea Mara, Seeger Michael, Navia Rodrigo. 2020. Applications of electrospun nanofibers with antioxidant properties: A review. Nanomaterials 10: 175; 
  25. Sanhueza Claudia, Diaz-Rodriguez Patricia, Villegas Pamela, González, Angela, Seeger Michael, Suárez-González Javier, Concheiro Angel, Alvarez-Lorenzo Carmen, Acevedo Francisca. 2020. Influence of carbon source on the properties of poly-(3)-hydroxybutyrate produced by Paraburkholderia xenovorans LB400 and its electrospun fibers. International Journal of Biological Macromolecules 152:11-20. 
  26. Bravo Guillermo, Vega-Celedón Paulina, Gentina Juan Carlos, Seeger Michael. 2020. Effects of mercury II on Cupriavidus metallidurans strain MSR33 during mercury bioremediation under aerobic and anaerobic conditions. Processes 2020, 8(8), 893; 
  27. Bravo Guillermo, Vega-Celedón Paulina, Gentina Juan Carlos, Seeger Michael. 2020. Bioremediation by Cupriavidus metallidurans strain MSR33 of mercury-polluted agricultural soil in a rotary drum bioreactor and its effects on nitrogen cycle microorganisms. Microorganisms. 8:1952. 
  28. Dorta Fernando, Polanco Víctor, Ramírez Ingrid, Seeger Michael, Madrid Alejandro, Montenegro Iván. 2020. In vitro propagation of Leptocarpha rivularis, a native medicinal plant. In Vitro Cellular & Developmental Biology - Plant. 
  29. Farkas C, Donoso RA, Melis-Arcos F, Gárate-Castro C, Pérez-Pantoja D. Complete Genome Sequence of Rhodococcus ruber R1, a Novel Strain Showing a Broad Catabolic Potential toward Lignin-Derived Aromatics. Microbiol Resour Announc. 2020 Jan 9;9(2):e00905-19. 
  30. Lamprecht-Grandío M, Cortesão M, Mirete S, de la Cámara MB, de Figueras CG, Pérez-Pantoja D, White JJ, Farías ME, Rosselló-Móra R, González-Pastor JE. Novel Genes Involved in Resistance to Both Ultraviolet Radiation and Perchlorate From the Metagenomes of Hypersaline Environments. Front Microbiol. 2020 Mar 26;11:453. eCollection 2020. 
  31. González, V.; Vargas-Straube, M.J.; Beys-da-Silva, W.O.; Santi, L.; Valencia, P.; Beltrametti, F.; Cámara, B. Enzyme Bioprospection of Marine-Derived Actinobacteria from the Chilean Coast and New Insight in the Mechanism of Keratin Degradation in Streptomyces sp. G11C. Mar. Drugs 2020, 18, 537. 
  32. Larach Alejandra, Torres Carolina, Riquelme Natalia, Valenzuela Miryam, Salgado Eduardo, Seeger Michael, and Besoain Ximena. 2020. Damage estimation and pathogen identification of Botryosphaeria dieback in Chilean vineyards cv. Cabernet Sauvignon in two different years. Phytopathology Mediterranea, vol. 59, no. 3, pp. 537-548, Dec. 2020. . 
  33. Méndez Valentina, Valenzuela Miryam, Salvà-Serra Francisco, Jaén-Luchoro Daniel, Besoain Ximena, Moore Edward R. B. & Seeger Michael. 2020. Comparative genomics of pathogenic Clavibacter michiganensis subsp. michiganensis strains from Chile reveals potential virulence features for tomato plants. Microorganisms 8:1679. 
  34. Vega-Celedón P, Bravo G, Velásquez A, Cid FP, Valenzuela M, Ramírez I, Vasconez I-N, Álvarez I, Jorquera MA, Seeger M. Microbial Diversity of Psychrotolerant Bacteria Isolated from Wild Flora of Andes Mountains and Patagonia of Chile towards the Selection of Plant Growth-Promoting Bacterial Consortia to Alleviate Cold Stress in Plants. Microorganisms. 2021; 9(3):538. 
  35. Montenegro Iván, Moreira Jorge, Ramirez Ingrid, Dorta Fernando, Sanchez Elizabeth, Alfaro Felipe, Valenzuela Manuel, Jara Carlos, Muñoz Ociel, Alvear Matias, Werner Enrique, Madrid Alejandro, Villena Joan, Seeger Michael. 2021. Chemical composition, antioxidant and anticancer activities of Leptocarpha rivularis DC flower extracts. Molecules 26: 67 
  36. Orellana, R.; Arancibia, A.; Badilla, L.; Acosta, J.; Arancibia, G.; Escar, R.; Ferrada, G.; Seeger, M. Ecophysiological Features Shape the Distribution of Prophages and CRISPR in Sulfate Reducing Prokaryotes. Microorganisms 2021, 9, 931. 
  37. Raúl A.DonosoabFabiánGonzález-ToroaDaniloPérez-Pantojaa. Widespread distribution of hmf genes in Proteobacteria reveals key enzymes for 5-hydroxymethylfurfural conversion. Computational and Structural Biotechnology JournalVolume 19, 2021, Pages 2160-2169. 
  38. Ariel Vilchez, Francisca Acevedo, Mara Cea, Michael Seeger, Rodrigo Navia. 2021. Development and thermochemical characterization of an antioxidant material based on polyhydroxybutyrate electrospun microfibers. International Journal of Biological Macromolecules. Volume 183, Pages 772-780, ISSN 0141-8130, 
  39. Sankaranarayanan S., Hariram M., Vivekanandhan S. & Navia R. 2021 Sustainable biocarbon materials derived from Lessonia Trabeculata macroalgae biomass residue for supercapacitor applications. Energy Storage. Energy StorageVolume 3, Issue 2 e222. 
  40. Gonzalez K., Navia R., Liu S. & Cea M. 2021 Biological approaches in polyhydroxyalkanoates recovery. Current Microbiology 78, 1-10.
  41. Claudia Sanhueza, Jeyson Hermosilla, Ana Bugallo-Casal, Andrés Da Silva-Candal, Cristina Taboada, Rosendo Millán, Angel Concheiro, Carmen Alvarez-Lorenzo, Francisca Acevedo. 2020. One-step electrospun scaffold of dual-sized gelatin/poly-3-hydroxybutyrate nano/microfibers for skin regeneration in diabetic wound. Materials Science and Engineering: C. Volume 119, 111602 
  42. Francisco Salvà-Serra, Raúl Donoso-Luna, Kyoung Hee Cho, Ji A Yoo, Kihyun Lee, Seok-Hwan Yoon, Beatriz Piñeiro-Iglesias, Edward Moore, and Danilo Pérez-Pantoja 2021. Complete multipartite genome sequence of Cupriavidus basilensis type strain: a 2,6-dichlorophenol-degrading bacterium. Microbiology Resource Announcement. 
  43. Natalia Alvarez-Santullano, Pamela Villegas, Mario Sepúlveda M, Roberto E. Durán, Raúl Donoso, Angela González, Claudia Sanhueza, Rodrigo Navia, Francisca Acevedo, Danilo Pérez-Pantoja, Michael Seeger. 2021. Genome-wide metabolic reconstruction of the synthesis of polyhydroxyalkanoates from sugars and fatty acids by Burkholderia sensulato species. Microorganisms. 2021 Jun 12;9(6):1290. 
  44. Valencia R, González V, Undabarrena A, Zamora-Leiva L, Ugalde JA, Cámara B. An Integrative Bioinformatic Analysis for Keratinase Detection in Marine-Derived Streptomyces. Marine Drugs. 2021; 19(6):286.
  45. Undabarrena A, Valencia R, Cumsille A, Zamora-Leiva L, Castro-Nallar E, Barona-Gómez F, Cámara B. 2021 Evolutionary genomics of the Rhodococcus genus reveals phylogenomic-dependent ancestral natural product biosynthetic traits. MICROBIAL GENOMICS Volume 7, Issue 7. 
  46. Rojas-Gätjens, D., Fuentes-Schweizer, P., Rojas-Jiménez, K., Pérez-Pantoja, D., Avendaño, R., Alpízar, R., Coronado-Ruiz, C., Chavarría, M. 2021. Methylotrophs and Hydrocarbon-Degrading Bacteria Are Key Players in the Microbial Community of an Abandoned Century-Old Oil Exploration Well. Microb Ecol (2021). 
  47. Akkaya, Ö., Aparicio, T., Pérez-Pantoja, D. and de Lorenzo, V. (2021), The faulty SOS response of Pseudomonas putida KT2440 stems from an inefficient RecA-LexA interplay. 2021 Environ Microbiol, 23: 1608-1619. 
  48. Pérez-Pantoja D, Nikel PI, Chavarría M, de Lorenzo V. Transcriptional control of 2,4-dinitrotoluene degradation in Burkholderia sp. R34 bears a regulatory patch that eases pathway evolution. Environ Microbiol. 2021 PMID: 33734558. 
  49. Raúl A. Donoso, Daniela Ruiz, Carla Gárate-Castro, Pamela Villegas, José Eduardo González-Pastor, Víctor de Lorenzo, Bernardo González, Danilo Pérez-Pantoja. 2021. Identification of a self-sufficient cytochrome P450 monooxygenase from Cupriavidus pinatubonensis JMP134 involved in 2-hydroxyphenylacetic acid catabolism, via homogentisate pathway. Microb. Biotechnol. (2021) 00( 00), 1- 17 

Tesis finalizadas 2018-2020

Lisette Hernández - Ingeniera Civil Ambiental, Universidad Técnica Federico Santa María

Aislamiento y caracterización de una bacteria hidrocarbonoclástica de la Región de Valparaíso y su aplicación en biorremediación de hidrocarburos. 

Pablo Alviz - Doctor en Ciencias Mención Microbiología, Universidad de Chile

Caracterización de la vía del c-di-GMP en la formación de biopelículas y la resistencia a Cadmio en Cupriavidus metallidurans CH34.

Roberto Durán - Magíster en Bioquímica, Especialización en Bioquímica Ambiental, Universidad de Chile

Caracterización genómica y funcional del catabolismo de hidrocarburos aromáticos en la bacteria marina Alcaligenes aquatilis QD168 y estudio de la respuesta adaptativa a estrés oxidativo durante la degradación de benceno.

Natalia Álvarez-Santullano - Ingeniera Civil Química, Universidad Técnica Federico Santa María 

Producción de poli(3-hidroxibutirato) por la cepa Burkholderia xenovorans LB400.

Miryam Valenzuela - Doctora en Biotecnología, Universidad Técnica Federico Santa María, Pontificia Universidad Católica de Valparaíso 

Caracterización de cepas del fitopatógeno de tomate Clavibacter michiganensis subsp. michiganensis aisladas en Chile y estrategias de biocontrol.

Bárbara Barra  - Doctora en Biotecnología, Universidad Técnica Federico Santa María, Pontificia Universidad Católica de Valparaíso

Efecto de la bioestimulación con saponinas de Quillaja saponaria Molina y la Bioaumentación con un consorcio bacteriano sobre la degradación de hidrocarburos y las comunidades microbianas en agua marina contaminada. 

Juan Felipe Alfaro - Doctor en Biotecnología, Universidad Técnica Federico Santa María, Pontificia Universidad Católica de Valparaíso

Efecto del portainjerto de tomane INIA sobre los mecanismos de defensa fisiológicos de la planta injertada de tomate limachino durante la infección por Pseudomonas syringae pv. tomato.

Paulina Vega Celedón - Doctora en Biotecnología, Universidad Técnica Federico Santa María, Pontificia Universidad Católica de Valparaíso

Efecto de un consorcio de bacterias psicrotolerantes promotoras del crecimiento vegetal sobre plantas de interés productivo de Chile afectados por las bajas temperaturas

Alexis Velásquez Sáez - Doctor en Biotecnología, Universidad Técnica Federico Santa María, Pontificia Universidad Católica de Valparaíso

Effect of arbuscular mycorrhizal fungi and plant growth-promoting rhizobacteria on volatile organic compounds in Vitis vinifera L.

Francisca Olivares Vargas - Ingeniera Civil Ambiental, Universidad Técnica Federico Santa María

Caracterización del crecimiento en bioreactor de las cepas Pseudomonas sp. CpR2b y TmR8 para la producción de un bioinsumo promotor del crecimiento vegetal. 

Marcelo Araya Nail - Ingeniero en Biotecnología, Universidad Tecnológica Metropolitana

Construcción de una genoteca plurigenómica a partir de microorganismos tolerantes a inhibidores derivados de material lignocelulósico y selección funcional de genes de tolerancia 

Ángela González - Ingeniera Civil Química, Universidad Técnica Federico Santa María

Evaluación de la producción de polihidroxialcanoatos a partir de residuos agroindustriales por las cepas Paraburkholderia xenovorans LB400, Janthinobacterium sp. BmR6b y Pseudomonas sp. LC43.

Mauricio Guajardo Parra - Ingeniero en Biotecnología, Universidad Tecnológica de Chile INACAP

Selección funcional de genes de tolerancia desde una genoteca plurigenómica construida a partir de microorganismos tolerantes a inhibidores derivados de material lignocelulósico.