PUBLICACIONES CIENTÍFICAS 

Líneas de investigación, publicaciones y tesis finalizadas.

Líneas de investigación

  • Bioproducts for sustainable development, agriculture, and food industry

  • Biodegradation for clean-up of polluted environments

 Publicaciones 2018-2020

  1. Urtuvia Viviana, Villegas Pamela, Fuentes Sebastián, González Myriam, Seeger Michael. 2018. Burkholderia xenovorans LB400 possess a functional polyhydroxyalkanoate anabolic pathway and synthesizes poly(3-hydroxybutyrate) under nitrogen-limiting conditions. International Microbiology 21: 47. https://doi.org/10.1007/s10123-018-0004-3 
  2. Montenegro Iván, Madrid Alejandro, Cuellar Mauricio, Seeger Michael, Alfaro Juan Felipe, Besoain Ximena, Martínez Juan Pablo, Ramirez Ingrid, Olguín, Yusser, Valenzuela, Miryam. 2018. Biopesticide activity from drimanic compounds to control tomato pathogens. Molecules. 16: 23(8). https://doi.org/10.3390/molecules23082053 
  3. Orellana Roberto, Macaya Constanza, Bravo Guillermo, Dorochesi Flavia, Cumsille Andrés, Valencia Ricardo, Rojas Claudia, Seeger Michael. 2018. Living at the frontiers of life: extremophiles in Chile and their potential for bioremediation. Frontiers in Microbiology 9:1-24. https://doi.org/10.3389/fmicb.2018.02309 
  4. Méndez Valentina, Hernández Lisette, Salvà-Serra Francisco, Jaén-Luchoro, Daniel, Durán, Roberto E., Barra Bárbara, Piñeiro-Iglesias Beatriz, Moore, Edward R. B., Seeger Michael 2018. Complete genome sequence of the hydrocarbon-degrading strain Achromobacter sp. B7, isolated during petroleum hydrocarbon bioremediation in Valparaiso Region, Chile. Microbiology Resource Announcements. 7:e01326-18. https://doi.org/10.1128/MRA.01326-18 
  5. Concha Eric, Heipieper Hermann J, Wick Lukas Y, Ciudad Gustavo A, Navia Rodrigo. 2018. Effects of limonene, n‑decane and n‑decanol on growth and membrane fatty acid composition of the microalga Botryococcus braunii. AMB Express 8:189. https://doi.org/10.1186/s13568-018-0718-9 
  6. Valenzuela Miryam, Méndez Valentina, Montenegro Iván, Besoain Ximena, Seeger Michael. 2019. Streptomycin resistance in Clavibacter michiganensis subsp. michiganensis Chilean strains is related to rpsL gene mutation. Plant Pathology 68: 426-433. https://doi.org/10.1111/ppa.12971 
  7. Durán RE, Barra-Sanhueza B, Salvà-Serra F, Méndez V, Jaén-Luchoro D, Moore ERB, Seeger M. 2019. Complete genome sequence of the marine hydrocarbon degrader Alcaligenes aquatilis QD168, isolated from crude oil-polluted sediment of Quintero Bay, Central Chile. Microbiol Resour Announc 8:e01664-18. https://doi.org/10.1128/MRA.01664-18 
  8. Sanhueza C., Acevedo F., Rocha S., Villegas, P., Seeger M., Navia R. 2019. Polyhydroxyalkanoates as biomaterial for an electrospun scaffold. International Journal of Biological Macromolecules 124: 102-110 https://doi.org/10.1016/j.ijbiomac.2018.11.068 
  9. Durán Roberto E., Méndez Valentina, Barra-Sanhueza Bárbara, Rodríguez-Castro Laura, Salvà-Serra Francisco, Moore Edward R. B., Castro-Nallar, Eduardo, Seeger, Michael. 2019. Genomic and physiological traits of the marine bacterium Alcaligenes aquatilis QD168 isolated from Quintero Bay, Central Chile, reveal a robust adaptive response to environmental stressors. Frontiers in Microbiology 10: 528. https://doi.org/10.3389/fmicb.2019.00528 
  10. Alviz Gazitua Pablo, Fuentes-Albuquerque Sebastian, Rojas Luis A., Turner Raymond J, Guiliani Nicolas, Seeger Michael. 2019. The response of Cupriavidus metallidurans CH34 to cadmium involves inhibition of the initiation of biofilm formation, decrease in intracellular c-di-GMP levels and a novel metal regulated phosphodiesterase. Frontiers in Microbiology, Front. Microbiol. 10:1499. https://doi.org/10.3389/fmicb.2019.01499 
  11. Macaya CC, Méndez V, Durán RE, Aguila-Torres P, Salvà-Serra F, Jaén-Luchoro D, Moore ERB, Seeger M. 2019. Complete genome sequence of hydrocarbon-degrading halotolerant Acinetobacter radioresistens DD78, isolated from the Aconcagua River mouth in Central Chile. Microbiol Resour Announc 8:e00601-19. https://doi.org/10.1128/MRA.00601-19 
  12. Rodríguez-Castro Laura, Méndez Valentina, Durán Roberto E., Seeger Michael 2019. Long-chain flavodoxin FldX1 improves Paraburkholderia xenovorans LB400 tolerance to oxidative stress caused by paraquat and H2O2. PLoS ONE. 14(8): e0221881. https://doi.org/10.1371/journal.pone.0221881 
  13. Claverías F, Gonzales-Siles L, Salvà-Serra F, Inganäs E, Molin K, Cumsille A, Undabarrena A, Couve E, Moore ERB, Gomila M, Cámara B. 2019 Corynebacterium alimapuense sp. nov., an obligate marine actinomycete isolated from sediment of Valparaíso bay, Chile. IJSEM 69(3):783-790. https://doi.org/10.1099/ijsem.0.003237 
  14. Cea Mara, Gonzáleza, María Eugenia, Abarzúa Macarena, Navia Rodrigo 2019. Enzymatic esterification of oleic acid by Candida rugosa lipase immobilized onto biochar. Journal of Environmental Management 242: 171-177. https://doi.org/10.1016/j.jenvman.2019.04.013 
  15. Hidalgo P, Navia R, Hunterd R, Gonzalez ME, Echeverría A. 2019. Development of novel bio-based epoxides from microalgae Nannochloropsis gaditana lipids. Composites Part B 166:653-662. https://doi.org/10.1016/j.compositesb.2019.02.049 
  16. Hildago-Oporto Pamela, Navia R, Hunter R, Coronado G, Gonzalez ME. 2019. Synthesis of carbon nanotubes using biochar as precursor material under microwave irradiation. Journal of Environmental Management 244:83-91. https://doi.org/10.1016/j.jenvman.2019.03.082 
  17. Sankaranarayanan Sivashunmugam, Likozar Blaž, Navia Rodrigo. 2019. Real-time particle size analysis using the Focused Beam Reflectance Measurement probe for in situ fabrication of polyacrylamide-filler composite materials. Scientific Reports 9:10126. https://doi.org/10.1038/s41598-019-46451-x 
  18. Sankaranarayanan, S., Vishnukumar, P., Hariram, M., Vivekanandhan, S., Camus, C., Buschmann, A.H. and Navia, R. 2019. Hydrothermal synthesis, characterization and seed germination effects of green‐emitting graphene oxide‐carbon dot composite using brown macroalgal bio‐oil as precursor. J. Chem. Technol. Biotechnol., 94: 3269-3275. https://doi.org/10.1002/jctb.6137 
  19. Akkaya Ö, Nikel PI, Pérez-Pantoja D, de Lorenzo V. Evolving metabolism of 2,4-dinitrotoluene triggers SOS-independent diversification of host cells. Environ Microbiol. 2019 21(1):314-326. https://doi.org/10.1111/1462-2920.14459 
  20. Farkas Carlos, Donoso Raúl, Gárate-Castro Carla, Villegas Pamela, Durán Roberto E, Seeger Michael, Pérez-Pantoja, Danilo 2020. Draft genome sequence of two Pseudomonas strains that are able to use furan derivatives as only carbon source. Microbiology Resource Announcements 9:e01131-19. https://doi.org/10.1128/MRA.01131-19 
  21. Vasconez Ingrid Nicole, Besoain Ximena A., Vega-Celedón Paulina, Valenzuela Miryam, Seeger Michael. 2020, First Report of Bacterial Wilt Caused by Ralstonia solanacearum Phylotype IIB Sequevar 1 affecting tomato in different Regions of Chile. Plant Disease. Published Online: 11 Mar 2020. https://doi.org/10.1094/PDIS-01-20-0181-PDN 
  22. Velásquez A, Vega-Celedón P, Fiaschi G, Agnolucci M, Avio L, Giovannetti M, D'Onofrio C, Seeger M. 2020. Responses of Vitis vinifera cv. Cabernet Sauvignon roots to the arbuscular mycorrhizal fungus Funneliformis mosseae and the plant growth-promoting rhizobacterium Ensifer meliloti include changes in volatile organic compounds. Mycorrhiza volume 30, pages 161-170(2020). https://doi.org/10.1007/s00572-020-00933-3 
  23. Velásquez Alexis, Valenzuela Miryam, Carvajal Marcela, Fiaschi Grazia, Avio Luciano, Giovannetti Manuela, D'Onofrio Claudio, Seeger Michael. 2020. The arbuscular mycorrhizal fungus Funneliformis mosseae induces changes and increases the concentration of volatile organic compounds in Vitis vinifera cv. Sangiovese leaf tissue. Plant Physiology and Biochemistry 155: 437-443. https://doi.org/10.1016/j.plaphy.2020.06.048 
  24. Vilchez Ariel, Acevedo Francisca, Cea Mara, Seeger Michael, Navia Rodrigo. 2020. Applications of electrospun nanofibers with antioxidant properties: A review. Nanomaterials 10: 175; https://doi.org/10.3390/nano10010175   
  25. Sanhueza Claudia, Diaz-Rodriguez Patricia, Villegas Pamela, González, Angela, Seeger Michael, Suárez-González Javier, Concheiro Angel, Alvarez-Lorenzo Carmen, Acevedo Francisca. 2020. Influence of carbon source on the properties of poly-(3)-hydroxybutyrate produced by Paraburkholderia xenovorans LB400 and its electrospun fibers. International Journal of Biological Macromolecules 152:11-20. https://doi.org/10.1016/j.ijbiomac.2020.02.080 
  26. Bravo Guillermo, Vega-Celedón Paulina, Gentina Juan Carlos, Seeger Michael. 2020. Effects of mercury II on Cupriavidus metallidurans strain MSR33 during mercury bioremediation under aerobic and anaerobic conditions. Processes 2020, 8(8), 893; https://doi.org/10.3390/pr8080893 
  27. Bravo Guillermo, Vega-Celedón Paulina, Gentina Juan Carlos, Seeger Michael. 2020. Bioremediation by Cupriavidus metallidurans strain MSR33 of mercury-polluted agricultural soil in a rotary drum bioreactor and its effects on nitrogen cycle microorganisms. Microorganisms. 8:1952. https://doi.org/10.3390/microorganisms8121952 
  28. Dorta Fernando, Polanco Víctor, Ramírez Ingrid, Seeger Michael, Madrid Alejandro, Montenegro Iván. 2020. In vitro propagation of Leptocarpha rivularis, a native medicinal plant. In Vitro Cellular & Developmental Biology - Plant. https://doi.org/10.1007/s11627-020-10097-6 
  29. Farkas C, Donoso RA, Melis-Arcos F, Gárate-Castro C, Pérez-Pantoja D. Complete Genome Sequence of Rhodococcus ruber R1, a Novel Strain Showing a Broad Catabolic Potential toward Lignin-Derived Aromatics. Microbiol Resour Announc. 2020 Jan 9;9(2):e00905-19. https://doi.org/10.1128/mra.00905-19 
  30. Lamprecht-Grandío M, Cortesão M, Mirete S, de la Cámara MB, de Figueras CG, Pérez-Pantoja D, White JJ, Farías ME, Rosselló-Móra R, González-Pastor JE. Novel Genes Involved in Resistance to Both Ultraviolet Radiation and Perchlorate From the Metagenomes of Hypersaline Environments. Front Microbiol. 2020 Mar 26;11:453. eCollection 2020. https://doi.org/10.3389/fmicb.2020.00453  
  31. González, V.; Vargas-Straube, M.J.; Beys-da-Silva, W.O.; Santi, L.; Valencia, P.; Beltrametti, F.; Cámara, B. Enzyme Bioprospection of Marine-Derived Actinobacteria from the Chilean Coast and New Insight in the Mechanism of Keratin Degradation in Streptomyces sp. G11C. Mar. Drugs 2020, 18, 537.https://doi.org/10.3390/md18110537 
  32. Larach Alejandra, Torres Carolina, Riquelme Natalia, Valenzuela Miryam, Salgado Eduardo, Seeger Michael, and Besoain Ximena. 2020. Damage estimation and pathogen identification of Botryosphaeria dieback in Chilean vineyards cv. Cabernet Sauvignon in two different years. Phytopathology Mediterranea, vol. 59, no. 3, pp. 537-548, Dec. 2020. https://doi.org/10.14601/Phyto-11235. https://oajournals.fupress.net/index.php/pm/article/view/11235.
  33. Méndez Valentina, Valenzuela Miryam, Salvà-Serra Francisco, Jaén-Luchoro Daniel, Besoain Ximena, Moore Edward R. B. & Seeger Michael. 2020. Comparative genomics of pathogenic Clavibacter michiganensis subsp. michiganensis strains from Chile reveals potential virulence features for tomato plants. Microorganisms 8:1679. https://doi.org/10.3390/microorganisms8111679 
  34. Vega-Celedón P, Bravo G, Velásquez A, Cid FP, Valenzuela M, Ramírez I, Vasconez I-N, Álvarez I, Jorquera MA, Seeger M. Microbial Diversity of Psychrotolerant Bacteria Isolated from Wild Flora of Andes Mountains and Patagonia of Chile towards the Selection of Plant Growth-Promoting Bacterial Consortia to Alleviate Cold Stress in Plants. Microorganisms. 2021; 9(3):538. https://doi.org/10.3390/microorganisms9030538 
  35. Montenegro Iván, Moreira Jorge, Ramirez Ingrid, Dorta Fernando, Sanchez Elizabeth, Alfaro Felipe, Valenzuela Manuel, Jara Carlos, Muñoz Ociel, Alvear Matias, Werner Enrique, Madrid Alejandro, Villena Joan, Seeger Michael. 2021. Chemical composition, antioxidant and anticancer activities of Leptocarpha rivularis DC flower extracts. Molecules 26: 67 https://doi.org/10.3390/molecules26010067 
  36. Orellana, R.; Arancibia, A.; Badilla, L.; Acosta, J.; Arancibia, G.; Escar, R.; Ferrada, G.; Seeger, M. Ecophysiological Features Shape the Distribution of Prophages and CRISPR in Sulfate Reducing Prokaryotes. Microorganisms 2021, 9, 931. https://doi.org/10.3390/microorganisms9050931  
  37. Raúl A.DonosoabFabiánGonzález-ToroaDaniloPérez-Pantojaa. Widespread distribution of hmf genes in Proteobacteria reveals key enzymes for 5-hydroxymethylfurfural conversion. Computational and Structural Biotechnology JournalVolume 19, 2021, Pages 2160-2169. https://doi.org/10.1016/j.csbj.2021.04.017 

Tesis finalizadas 2018-2020

Lisette Hernández - Ingeniera Civil Ambiental, Universidad Técnica Federico Santa María

Aislamiento y caracterización de una bacteria hidrocarbonoclástica de la Región de Valparaíso y su aplicación en biorremediación de hidrocarburos. 


Pablo Alviz - Doctor en Ciencias Mención Microbiología, Universidad de Chile

Caracterización de la vía del c-di-GMP en la formación de biopelículas y la resistencia a Cadmio en Cupriavidus metallidurans CH34.

Roberto Durán - Magíster en Bioquímica, Especialización en Bioquímica Ambiental, Universidad de Chile

Caracterización genómica y funcional del catabolismo de hidrocarburos aromáticos en la bacteria marina Alcaligenes aquatilis QD168 y estudio de la respuesta adaptativa a estrés oxidativo durante la degradación de benceno.

Natalia Álvarez-Santullano - Ingeniera Civil Química, Universidad Técnica Federico Santa María 

Producción de poli(3-hidroxibutirato) por la cepa Burkholderia xenovorans LB400.


Miryam Valenzuela - Doctora en Biotecnología, Universidad Técnica Federico Santa María, Pontificia Universidad Católica de Valparaíso 

Caracterización de cepas del fitopatógeno de tomate Clavibacter michiganensis subsp. michiganensis aisladas en Chile y estrategias de biocontrol.


Bárbara Barra  - Doctora en Biotecnología, Universidad Técnica Federico Santa María, Pontificia Universidad Católica de Valparaíso

Efecto de la bioestimulación con saponinas de Quillaja saponaria Molina y la Bioaumentación con un consorcio bacteriano sobre la degradación de hidrocarburos y las comunidades microbianas en agua marina contaminada. 


Juan Felipe Alfaro - Doctor en Biotecnología, Universidad Técnica Federico Santa María, Pontificia Universidad Católica de Valparaíso

Efecto del portainjerto de tomane INIA sobre los mecanismos de defensa fisiológicos de la planta injertada de tomate limachino durante la infección por Pseudomonas syringae pv. tomato.


Paulina Vega Celedón - Doctora en Biotecnología, Universidad Técnica Federico Santa María, Pontificia Universidad Católica de Valparaíso

Efecto de un consorcio de bacterias psicrotolerantes promotoras del crecimiento vegetal sobre plantas de interés productivo de Chile afectados por las bajas temperaturas


Alexis Velásquez Sáez - Doctor en Biotecnología, Universidad Técnica Federico Santa María, Pontificia Universidad Católica de Valparaíso

Effect of arbuscular mycorrhizal fungi and plant growth-promoting rhizobacteria on volatile organic compounds in Vitis vinifera L.


Francisca Olivares Vargas - Ingeniera Civil Ambiental, Universidad Técnica Federico Santa María

Caracterización del crecimiento en bioreactor de las cepas Pseudomonas sp. CpR2b y TmR8 para la producción de un bioinsumo promotor del crecimiento vegetal. 


Marcelo Araya Nail - Ingeniero en Biotecnología, Universidad Tecnológica Metropolitana

Construcción de una genoteca plurigenómica a partir de microorganismos tolerantes a inhibidores derivados de material lignocelulósico y selección funcional de genes de tolerancia 


Ángela González - Ingeniera Civil Química, Universidad Técnica Federico Santa María

Evaluación de la producción de polihidroxialcanoatos a partir de residuos agroindustriales por las cepas Paraburkholderia xenovorans LB400, Janthinobacterium sp. BmR6b y Pseudomonas sp. LC43.


Mauricio Guajardo Parra - Ingeniero en Biotecnología, Universidad Tecnológica de Chile INACAP

Selección funcional de genes de tolerancia desde una genoteca plurigenómica construida a partir de microorganismos tolerantes a inhibidores derivados de material lignocelulósico.